Vaccine in September?

Discussion in 'Bulletin Board' started by Farnham_Red, Apr 21, 2020.

  1. SuperTyke

    SuperTyke Well-Known Member

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    They are monitored and have tests done to check for side effects and general health while also checking for antibodies because if you produce no antibodies then the vaccine isn't working.
    If serious side effects appear then the trial is obviously ended.

    They set off with low levels as it's less dangerous and will monitor. If no side effects are shown they use a stronger version of the vaccine until it gets to the point that they are testing people with one that is strong enough to produce enough antibodies that they believe would provide a level of immunity.

    They do it on a small scale, then a larger and then an even larger
     
  2. Red

    Redsnut Well-Known Member

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    Thanks for your help guys just one more question will e-red be able to tell us what’s happening or are you sworn to secrecy.
     
  3. Red

    Red-Taff. Well-Known Member

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    google 'how vaccines are licensed and monitored'


    I would be very surprised if a meningitis vaccine would be part of the Covid 19 vaccine. It would be unethical to use such a powerful vaccine.
    Usually in double blind trials half a group will be given the drug/vaccine being tested the other half a placebo but the participants and the staff running these trials don't know who is on what.

    The present volunteers will be vaccinated to find out if people can actually survive being vaccinated with a Covid 19 vaccine.
    This is step 1.
    If it's not lethal then more intense developing and testing will take place - some drugs/vaccines affect the liver or other organs so the testing has to in depth - not just a matter of seeing I antibodies are developed.

    as I wrote earlier google <how vaccines are tested, licensed and monitored> to see how complicated and time consuming the process is.
     
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  4. dreamboy3000

    dreamboy3000 Well-Known Member

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    This is one link mentioning a meningitis vaccine for half the group......

    https://www.independent.co.uk/news/...eatment-trial-oxford-university-a9472831.html

    Vaccines take years usually but we don't have years. I'm sure more people will risk taking it than won't. Over 80 possible vaccines are being looked at so hopefully as many as possible work. Blood plasma of a survivor being used seems a good one but you don't know how long it will last for. Fingers crossed there is something in the MMR vaccine that works.

    https://www.dailymail.co.uk/news/ar...rotect-against-coronavirus-complications.html
     
  5. Jay

    Jay Well-Known Member

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    Up to the 10th April 10,350 Covid-19 related deaths had been registered in the UK. 8,998 of those were people aged 65 or above. Only 126 were people aged 45 or below. It's difficult for me to understand why anyone, certainly under the age of 45, but realistically anyone of any age who is healthy and reasonably fit, would be vaccinated with a substance that hasn't gone though the usual vigorous testing.

    https://www.ons.gov.uk/peoplepopula...articles/coronaviruscovid19roundup/2020-03-26

    I also have amazing respect for anyone who volunteers in medical trials.
     
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  6. e-red

    e-red Well-Known Member

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    I don’t know whether I’ll be picked or what the criteria is. So it’s a bit early to say. I filled in a questionnaire and they’ll decide.
     
  7. Redstone

    Redstone Well-Known Member

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    And finding a effective treatment could in theory be much quicker to roll out than a vaccine. Let's hope something is found.
     
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  8. Jul

    Julian Broddle's Perm Well-Known Member

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    Total fair play to you, here mate, for volunteering.
    This may seem a bit of a naive question, but you will either know the answer or thought the same yourself. But, once injected (or otherwise) with the trial vaccine, do they then have to expose you to the virus / purposely give you a dose of it, to ensure it actually works?
    That’s not a flippant question, incidentally, far from it. But what if they vaccinated you, and others obviously, and you either don’t come into contact with the virus or have a natural immunity to it, thus making the vaccination ‘appear’ successful whilst not certainly the case.
     
  9. Red

    Red-Taff. Well-Known Member

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    were you asked if you'd had the anti-flu vaccine last Autumn?

    One worrying thing is that we now have older people and 'the vulnerable' succumbing to this virus in large numbers. It was the older and 'vulnerable' who were advised/encouraged to have the flu jab last autumn.
    Do those who had the flu-jab now have difficulty overcoming Covid19?
     
  10. SuperTyke

    SuperTyke Well-Known Member

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    That's not generally how it works. What they do is give you a vaccine and then measure the level of antibodies related to the virus that your body has generated as a result of the vaccination.
    I'm not sure how they know the level of antibodies required to give you immunity I don't think their aim is ever 100% immunity it's to have enough to give an acceptable level of immunity.
    They do it in small scale tests then much larger involving thousands of people so the natural immunity some could have will not distort the overall findings.
     
  11. SuperTyke

    SuperTyke Well-Known Member

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    I think you're missing the point of the flu jab connection. It isn't that having the flu jab makes you die of covid-19 it's that the people most vulnerable to a pneumonia style virus are given the flu jab.
    In other words 93 year old Gertrude from Gawber god bless her is unlikely to be able to fight off a virus that gives pneumonia related symptoms. She would struggle with covid-19 and struggle with flu too. If she caught covid-19 without a flu vaccination she would likely die, if she caught it with one she would likely die. Its simply that because she's so at risk of both that she's given a vaccine for one of them rather than it being a case that because she was given a vaccine it MAKES her more vulnerable to the other.

    Erm I think :)
     
  12. dreamboy3000

    dreamboy3000 Well-Known Member

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    Even if the vaccine works so many questions need answering such as will you only need to take it once in your lifetime or every X amount of time? Will older people need a bigger dose due to their older immune systems?
     
  13. e-red

    e-red Well-Known Member

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    The questionnaire was about my age and general condition and what health problems I may have. There was no detail about any potential risks, or exposure to the virus.
    My assumption is that if I am selected they will tell me more about it. It’s far too early to say anything, other than that if I weigh up the risks and still think I can help, then I will. I’m sure they have a lot of volunteers and I trust them to do the thing properly.
    I had a flu jab and a pneumonia jab in November and I don’t know what difference that may make.
     
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  14. SuperTyke

    SuperTyke Well-Known Member

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    Do you work for the NHS or are a carer e-red?
     
  15. e-red

    e-red Well-Known Member

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    No
     
  16. SuperTyke

    SuperTyke Well-Known Member

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    I was just looking at all the various trials that are ongoing and saw Cambridge were doing one specifically for frontline NHS staff.

    On a slightly related (and also slightly unrelated) note Oxford university have been doing a trial on a drug that is due to end tomorrow I think.
     
  17. e-red

    e-red Well-Known Member

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    I’m beginning to feel a bit odd about this, because some people think it’s a bit above and beyond to volunteer.
    You don’t have to answer, but at a time when so many are giving so much and I’m sat on my backside doing nowt. If you were asked to do something for the effort - would you?
     
    Last edited: Apr 22, 2020
  18. Hooky feller

    Hooky feller Well-Known Member

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    Hey up Jay. Just an update on the relative. I misunderstand the trial in the fact I thought it was before and after they were released. The trial was Steroids which have in the past been tested for other diseases/viruses. It happened whilst just in hospital. To relieve symptoms etc. One other thing that struck me was the fact they are not tested for the virus as such again before being released. ( not sure if that’s the same in every case they were not in the critical category, eg on oxygen not a ventilator) They base it on blood count. And other signs.
     
  19. BarnsleyReds

    BarnsleyReds Well-Known Member

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    I would. I think most people would.

    It’s still something that deserves praise, mate.
     
  20. SuperTyke

    SuperTyke Well-Known Member

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    I would. Honestly the levels they give people are all carefully thought out and it's done in the best environment possible
     

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